Important Safety Information
What Is ETHYOL Used For?
ETHYOL is a medication used in two ways.
- It is used to reduce your chances of kidney damage caused by cisplatin, a chemotherapy treatment, given for ovarian cancer.
- It is used to reduce dry mouth (xerostomia) caused by radiation treatment given for head and neck cancer.
What Does ETHYOL Do?
ETHYOL (amifostine) is a protective medicine. This medicine is given into your vein intravenously. It is given by a health care professional in a hospital or clinic setting.
What Should I Tell My Doctor Before Receiving Treatment With ETHYOL?
Before you receive ETHYOL, tell your doctor if you:
- Are taking a medicine called amifostine because it contains the same medicine as ETHYOL.
- Have had any unusual or allergic reactions to ETHYOL, other medicines, foods, dyes or preservatives.
- Have a history of heart disease.
- Have symptoms of low blood pressure or dehydration such as dizziness, fainting, nausea or blurred vision.
- Are dehydrated or have trouble passing urine or experience a change in the amount of urine
- Are taking blood pressure medications.
- Are at risk of low blood calcium (hypocalcemia).
- Are pregnant, plan to become pregnant, suspect you are pregnant, or are breastfeeding.
- Tell your doctor about all the medications you are taking, including prescription and over-the-counter medications and vitamins. Contact your doctor if you start any new prescription and over-the-counter medications and vitamins
What Are Some Important Things I Should Know When I Take ETHYOL?
- ETHYOL contains the same medicine as amifostine. If you are taking amifostine, do not take ETHYOL.
- If you are taking blood pressure medicine, your doctor may tell you to temporarily stop the day before your dose of ETHYOL.
- You should drink plenty of fluids before ETHYOL treatment.
What Side Effects Could Occur With ETHYOL?
- The most common side effects in patients receiving ETHYOL are low blood pressure, skin reactions, allergic reactions, upset stomach and vomiting, and low blood calcium.
- Life-threatening or serious allergic skin reactions have been reported. These reactions could happen weeks after you started ETHYOL. Tell your doctor right away if you get any of the following:
- rash, hives, skin lesions (blisters or peeling)
- itching or skin swelling with or without fever
- swollen lymph nodes
- feeling like you have the flu
- trouble breathing
- throat tightness
- swelling of the face, lips, or tongue
These are not all the possible side effects of ETHYOL. For more information and medical advice, ask your doctor or pharmacist.
You are encouraged to report the side effects of prescription drugs to the FDA.
- Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.
The risk information provided here is not complete.
- Talk to your doctor or nurse.
- Call 1-877-484-2700
- Click here to view Full Prescribing Information.